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Welcome to Tammi Lab

We address biological questions by computational and bioinformatics methods. The main research areas include gene regulation, in particular non-coding RNA, and emerging viruses.

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Highlights

AllerHunter picture AllerHunter: AllerHunter is a cross-reactive allergen prediction program built on a combination of Support Vector Machine (SVM) and pairwise sequence similarity. Cross-reactivity is based on similarity of proteins to allergens. However, not all proteins with similar sequence or structure to known allergens are cross-reactive allergens. AllerHunter aims to predict allergens and non-allergens with high sensitivity and specificity, without compromising efficiency at classification of proteins with similar sequence to known allergens. More ...

CNV-seq: a method to detect DNA copy number variation using the next-generation high-througput sequencing technologies. The method is based on a robust statistical model that describes the complete analysis procedure and allows the computation of essential confidence values for detection of CNV. More ...

microTar pic MicroTar: an animal miRNA target prediction tool based on miRNA-target complementarity and thermodynamic data. The algorithm uses predicted free energies of unbound mRNA and putative mRNA-miRNA heterodimers, implicitly addressing the accessibility of the mRNA 3-prime untranslated region. MicroTar does not rely on evolutionary conservation to discern functional targets, and is able to predict both conserved and non-conserved targets. More ...

DNPTrapper pic

DNPTrapper: DNPTrapper, a shotgun sequence finishing tool, designed to address the key sequence assembly problems caused by repeated regions in a genome. The program detects and visualizes single nucleotide differences between nearly identical repeat copies, and offers the overview and flexibility needed to rapidly resolve complex regions within a working session. The use of a database allows large amounts of data to be stored and handled, and allows viewing of mammalian size genomes. With DNPTrapper, it is possible to separate repeated regions that previously were considered impossible to resolve, and finishing tasks that previously took days or weeks can be resolved within hours or even minutes. The program is available under an Open Source license. More ...

Graduate studies. The admission guidelines are established by the University. The minimum reguirement for admission with Research Scholarship is a B.Sc. degree. The yearly applications deadlines are 15 November and 15 May. See information at
1) Department of Biological Sciences, Faculty of Science
2) Department of Biochemistry, Yong Loo Lin School of Medicine, Faculty of Medicine

Undergraduate research projects: We have always interesting projects in bioinformatics for Honours, UROPS and also projects during the vacation. Find out more ...

LMB 2007 Pic The International Conference on Bioinformatics (InCoB) is the official conference of the Asia-Pacific Bioinformatics Network (APBioNet). Beginning in 2002, it has grown to become one of the largest bioinformatics conference in the Asia-Pacific region. This annual conference showcases the latest research and technologies in all areas of bioinformatics and is attended by practitioners from both biology and computing backgrounds in the Asia-Pacific region. This year, InCoB will be held back to back with the Workshop on Education in Bioinformatics and Computational Biology (WEBCB), as well as the Singapore Symposium on Computational Biology (SYMBIO). Find Out More ...

Journals Pic OLS Bioinformatics For Biologists Seminar Series. This Seminar Series Is Aimed To Bring Biologists Together With Bioinformaticians And Computatinal Biologists.

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