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Database of Trypanosoma cruzi repeated genes The genome of Trypanosoma cruzi CL Brener is highly repetitive and polymorphic. This makes assembly and subsequent annotation of the genome difficult, and the current draft sequence is fragmented and lacks many copies of highly repetitive genes. We have studied all protein coding genes and pseudogenes in T. cruzi for alignment depth using a sensitive multiple alignment tool to build new alignments representing a gene and all its copies. A database of all annotated genes in Trypanosoma cruzi and their repetitive qualities has been created. It can be searched using a locus id or a GenBank id. The information includes estimation of copy number, collapses between annotated genes and, in many cases, repeat cassette information. [go to database] [Article]
Allergen Atlas is a comprehensive repository of experimentally validated allergen sequences that covers information from a wide range of protein families. Allergen names, sequences and related information were collected from literature reports, online data submission and all existing general-purpose and specialist databases. Each entry is manually verified, classified and hyperlinked to major databases including Swiss-Prot, PDB, GO, Pfam and PubMed. The database is integrated with a number of online analysis tools that include: (i) keyword search, (ii) BLAST, (iii) PSI-BLAST, (iv) FAO/WHO criteria search, (v) allergen information network and (vi) online data submission. The current release (version 1.0.0.) contains information of 1593 allergens: 496 IUIS allergens, 978 experimentally verified allergens, and 119 new sequences. [go to database]
BioMirrors databases and Specialty databases. A large number of other local databases, ranging from a collection of antimicrobial peptides, caspases and MHC-peptide interactions to scorpion toxins. Comprehensive link pages are maintained by NUS Bioinformatics Center.